| Reaction Details |
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 | Report a problem with these data |
| Target | Protein-arginine deiminase type-3 |
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| Ligand | BDBM50535205 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1929981 (CHEMBL4433157) |
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| IC50 | 12000±n/a nM |
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| Citation |  Jamali, H; Khan, HA; Tjin, CC; Ellman, JA Cellular Activity of New Small Molecule Protein Arginine Deiminase 3 (PAD3) Inhibitors. ACS Med Chem Lett7:847-51 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein-arginine deiminase type-3 |
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| Name: | Protein-arginine deiminase type-3 |
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| Synonyms: | PAD3 | PADI3 | PADI3_HUMAN | PDI3 | Peptidylarginine deiminase III | Protein-arginine deiminase type III |
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| Type: | PROTEIN |
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| Mol. Mass.: | 74727.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1290378 |
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| Residue: | 664 |
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| Sequence: | MSLQRIVRVSLEHPTSAVCVAGVETLVDIYGSVPEGTEMFEVYGTPGVDIYISPNMERGR
ERADTRRWRFDATLEIIVVMNSPSNDLNDSHVQISYHSSHEPLPLAYAVLYLTCVDISLD
CDLNCEGRQDRNFVDKRQWVWGPSGYGGILLVNCDRDDPSCDVQDNCDQHVHCLQDLEDM
SVMVLRTQGPAALFDDHKLVLHTSSYDAKRAQVFHICGPEDVCEAYRHVLGQDKVSYEVP
RLHGDEERFFVEGLSFPDAGFTGLISFHVTLLDDSNEDFSASPIFTDTVVFRVAPWIMTP
STLPPLEVYVCRVRNNTCFVDAVAELARKAGCKLTICPQAENRNDRWIQDEMELGYVQAP
HKTLPVVFDSPRNGELQDFPYKRILGPDFGYVTREPRDRSVSGLDSFGNLEVSPPVVANG
KEYPLGRILIGGNLPGSSGRRVTQVVRDFLHAQKVQPPVELFVDWLAVGHVDEFLSFVPA
PDGKGFRMLLASPGACFKLFQEKQKCGHGRALLFQGVVDDEQVKTISINQVLSNKDLINY
NKFVQSCIDWNREVLKRELGLAECDIIDIPQLFKTERKKATAFFPDLVNMLVLGKHLGIP
KPFGPIINGCCCLEEKVRSLLEPLGLHCTFIDDFTPYHMLHGEVHCGTNVCRKPFSFKWW
NMVP
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| BDBM50535205 |
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| n/a |
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| Name | BDBM50535205 |
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| Synonyms: | CHEMBL4461562 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21ClN4O |
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| Mol. Mass. | 344.839 |
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| SMILES | ClCC(=N)NCCNC(=O)NCc1cccc(c1)-c1ccccc1 |
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| Structure | 
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