| Reaction Details |
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 | Report a problem with these data |
| Target | Heme oxygenase 1 |
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| Ligand | BDBM50207199 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1930147 (CHEMBL4433398) |
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| IC50 | 1900±n/a nM |
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| Citation |  Salerno, L; Floresta, G; Ciaffaglione, V; Gentile, D; Margani, F; Turnaturi, R; Rescifina, A; Pittalą, V Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application. Eur J Med Chem167:439-453 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Heme oxygenase 1 |
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| Name: | Heme oxygenase 1 |
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| Synonyms: | HMOX1 | HMOX1_HUMAN | HO | HO-1 | HO1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32822.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_368941 |
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| Residue: | 288 |
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| Sequence: | MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVA
LEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHE
VGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQ
LYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRA
SNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATVAVGLYAM
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| BDBM50207199 |
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| n/a |
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| Name | BDBM50207199 |
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| Synonyms: | 1-((2-(2-(4-bromophenyl)ethyl)-1,3-dioxolan-2-yl)methyl)-1H-imidazole hydrochloride | CHEMBL539857 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H17BrN2O2 |
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| Mol. Mass. | 337.212 |
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| SMILES | Brc1ccc(CCC2(Cn3ccnc3)OCCO2)cc1 |
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| Structure | 
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