| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 4 |
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| Ligand | BDBM50535390 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1930330 (CHEMBL4433581) |
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| Ki | 3100±n/a nM |
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| Citation |  Bonardi, A; Vermelho, AB; da Silva Cardoso, V; de Souza Pereira, MC; da Silva Lara, L; Selleri, S; Gratteri, P; Supuran, CT; Nocentini, A -Nitrosulfonamides as Carbonic Anhydrase Inhibitors: A Promising Chemotype for Targeting Chagas Disease and Leishmaniasis. ACS Med Chem Lett10:413-418 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 4 |
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| Name: | Carbonic anhydrase 4 |
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| Synonyms: | CA-IV | CA4 | CAH4_HUMAN | Carbonate dehydratase IV | Carbonic anhydrase | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV) |
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| Type: | Enzyme |
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| Mol. Mass.: | 35037.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22748 |
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| Residue: | 312 |
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| Sequence: | MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTK
AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD
LPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGF
QPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFRE
PIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLG
PMLACLLAGFLR
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| BDBM50535390 |
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| n/a |
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| Name | BDBM50535390 |
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| Synonyms: | CHEMBL4558023 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H8AgN3O4S |
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| Mol. Mass. | 338.089 |
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| SMILES | [Ag;v0+].[#7]-[#6]-c1ccc(cc1)S(=O)(=O)[#7-]-[#7+](-[#8-])=O |
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| Structure | 
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