| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin F2-alpha receptor |
|---|
| Ligand | BDBM50091623 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_158459 (CHEMBL763263) |
|---|
| Ki | 1900±n/a nM |
|---|
| Citation |  Klimko, PG; Davis, TL; Griffin, BW; Sharif, NA Synthesis and biological activity of a novel 11a-homo (cyclohexyl) prostaglandin. J Med Chem43:3400-7 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin F2-alpha receptor |
|---|
| Name: | Prostaglandin F2-alpha receptor |
|---|
| Synonyms: | PF2R_HUMAN | PGF receptor | PGF2 alpha receptor | PGF2-alpha receptor | PTGFR | Prostaglandin F | Prostanoid FP receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 40072.29 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P43088 |
|---|
| Residue: | 359 |
|---|
| Sequence: | MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
RSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILD
PWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
|
|
|
|---|
| BDBM50091623 |
|---|
| n/a |
|---|
| Name | BDBM50091623 |
|---|
| Synonyms: | 7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-but-1-enyl]-3,6-dihydroxy-cyclohexyl}-hept-5-enoic acid | CHEMBL323591 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H31ClO6 |
|---|
| Mol. Mass. | 438.942 |
|---|
| SMILES | O[C@@H](COc1cccc(Cl)c1)\C=C\[C@H]1[C@H](O)CC[C@H](O)[C@@H]1C\C=C/CCCC(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
