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TargetAtrial natriuretic peptide receptor 3
LigandBDBM50091758
Substrate/Competitorn/a
Meas. Tech.ChEBML_34991
Ki 0.300000±n/a nM
Citation Veale CAAlford VCAharony DBanville DLBialecki RABrown FJDamewood JRDantzman CLEdwards PDJacobs RTMauger RCMurphy MMPalmer WPine KKRumsey WLGarcia-Davenport LEShaw ASteelman GBSurian JMVacek EP The discovery of non-basic atrial natriuretic peptide clearance receptor antagonists. Part 1. Bioorg Med Chem Lett 10:1949-52 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Atrial natriuretic peptide receptor 3
Name:Atrial natriuretic peptide receptor 3
Synonyms:ANP-C | ANPR-C | ANPRC | Atrial natriuretic peptide C-type receptor | Atrial natriuretic peptide clearance receptor | Atrial natriuretic peptide receptor | Atrial natriuretic peptide receptor C | C5orf23 | NPR-C | NPR3
Type:PROTEIN
Mol. Mass.:59805.12
Organism:Homo sapiens (Human)
Description:ChEMBL_34991
Residue:541
Sequence:
MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLP
QDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRV
AAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPA
YAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETK
DLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDG
SWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEG
FHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIA
MTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSSGGLE
ESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSV
A
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50091758
n/a
NameBDBM50091758
Synonyms:(S)-N-[(S)-4-Guanidino-1-((S)-2-methyl-butylcarbamoyl)-butyl]-3-{(2S,3S)-3-methyl-2-[(S)-2-(2-{4-[(naphthalene-2-carbonyl)-amino]-phenyl}-acetylamino)-propionylamino]-pentanoylamino}-succinamic acid | CHEMBL294263
TypeSmall organic molecule
Emp. Form.C43H59N9O8
Mol. Mass.829.9841
SMILESCC[C@H](C)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)Cc1ccc(NC(=O)c2ccc3ccccc3c2)cc1)[C@@H](C)CC
Structure
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