| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50092421 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_61577 (CHEMBL675091) |
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| IC50 | 2.3±n/a nM |
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| Citation |  Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T New substituted 1-(2,3-dihydrobenzo[1, 4]dioxin-2-ylmethyl)piperidin-4-yl derivatives with alpha(2)-adrenoceptor antagonist activity. J Med Chem43:3653-64 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50092421 |
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| n/a |
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| Name | BDBM50092421 |
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| Synonyms: | 1-(2,6-Dichloro-phenyl)-3-{2-[1-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-imidazolidin-2-one | CHEMBL121497 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29Cl2N3O3 |
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| Mol. Mass. | 490.422 |
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| SMILES | Clc1cccc(Cl)c1N1CCN(CCC2CCN(CC3COc4ccccc4O3)CC2)C1=O |
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| Structure | 
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