| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1B |
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| Ligand | BDBM34141 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1352 |
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| Ki | 9210±n/a nM |
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| Citation |  Tsai, Y; Dukat, M; Slassi, A; MacLean, N; Demchyshyn, L; Savage, JE; Roth, BL; Hufesein, S; Lee, M; Glennon, RA N1-(Benzenesulfonyl)tryptamines as novel 5-HT6 antagonists. Bioorg Med Chem Lett10:2295-9 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1B |
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| Name: | 5-hydroxytryptamine receptor 1B |
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| Synonyms: | 5-HT-1B | 5-HT-1D-beta | 5-HT1B | 5-hydroxytryptamine receptor 1B (5-HT1B) | 5HT1B_HUMAN | HTR1B | HTR1DB | S12 | Serotonin (5-HT) receptor | Serotonin 1D beta receptor | Serotonin Receptor 1B |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 43579.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Receptor binding assays were performed using human clone stably expressed in CHO cells |
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| Residue: | 390 |
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| Sequence: | MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALIT
LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
KQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLE
KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYL
NSLINPIIYTMSNEDFKQAFHKLIRFKCTS
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| BDBM34141 |
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| n/a |
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| Name | BDBM34141 |
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| Synonyms: | CHEMBL76237 | MS-245 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N2O3S |
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| Mol. Mass. | 358.455 |
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| SMILES | COc1ccc2n(cc(CCN(C)C)c2c1)S(=O)(=O)c1ccccc1 |
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| Structure | 
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