| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A |
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| Ligand | BDBM50537785 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1971475 (CHEMBL4604293) |
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| Kd | 7.9±n/a nM |
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| Citation |  Pan, BW; Shi, Y; Li, WC; Wang, Q; Pan, M; Wu, Q; Fu, HZ Synthesis and biological evaluation of Vinpocetine derivatives. Bioorg Med Chem Lett30:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A |
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| Name: | Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A |
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| Synonyms: | 61 kDa Cam-PDE | Calcium/calmodulin-dependent 3',5'-cyclic phosphodiesterase 1A | Cam-PDE 1A | PDE1A | PDE1A_HUMAN | hCam-1 |
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| Type: | Protein |
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| Mol. Mass.: | 61245.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P54750 |
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| Residue: | 535 |
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| Sequence: | MGSSATEIEELENTTFKYLTGEQTEKMWQRLKGILRCLVKQLERGDVNVVDLKKNIEYAA
SVLEAVYIDETRRLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMTKKKPEEKPKFRS
IVHAVQAGIFVERMYRKTYHMVGLAYPAAVIVTLKDVDKWSFDVFALNEASGEHSLKFMI
YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI
MHWLTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLM
QEEEMNILINLSKDDWRDLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPEGIDRAKTMSL
ILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGF
IDFIVEPTFSLLTDSTEKIVIPLIEEASKAETSSYVASSSTTIVGLHIADALRRSNTKGS
MSDGSYSPDYSLAAVDLKSFKNNLVDIIQQNKERWKELAAQEARTSSQKCEFIHQ
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| BDBM50537785 |
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| n/a |
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| Name | BDBM50537785 |
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| Synonyms: | CHEMBL4645801 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H28FN3OS |
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| Mol. Mass. | 461.594 |
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| SMILES | [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1cccc(F)c1)n1c2c(CC3)c2ccccc12 |r,t:10| |
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| Structure | 
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