| Reaction Details |
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 | Report a problem with these data |
| Target | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 |
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| Ligand | BDBM50539784 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1979331 (CHEMBL4612466) |
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| IC50 | 64820±n/a nM |
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| Citation |  Heger, V; Benesova, B; Viskupicova, J; Majekova, M; Zoofishan, Z; Hunyadi, A; Horakova, L Phenolic Compounds from ACS Med Chem Lett11:1006-1013 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 |
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| Name: | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 |
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| Synonyms: | AT2A1_RAT | Atp2a1 | Calcium pump 1 | Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform | Endoplasmic reticulum class 1/2 Ca(2+) ATPase | SERCA1 | SR Ca(2+)-ATPase 1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 109386.62 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_109814 |
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| Residue: | 994 |
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| Sequence: | MEAAHSKSTEECLSYFGVSETTGLTPDQVKRHLEKYGPNELPAEEGKSLWELVVEQFEDL
LVRILLLAACISFVLAWFEEGEETVTAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAVGIVATTGVSTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDKVDGDICSLNEFSITGSTYAPEGEVLKNDKPVRAGQYDGLVELATICALC
NDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRSLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP
VKEKIMSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSAKFMEYEMDLTFVGVVGML
DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFSENEEVADRAYTGREFDD
LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI
GGYVGAATVGAAAWWFLYAEDGPHVSYHQLTHFMQCTEHNPEFDGLDCEVFEAPEPMTMA
LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR
ALDFTQWLMVLKISLPVIGLDELLKFIARNYLEG
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| BDBM50539784 |
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| n/a |
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| Name | BDBM50539784 |
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| Synonyms: | CHEMBL1096940 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30O6 |
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| Mol. Mass. | 438.5128 |
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| SMILES | [#6]-[#8]-c1cc(-[#8])c(cc1-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6@@H]-1-[#6]-[#6](=O)-c2c(-[#8])cc(-[#8])cc2-[#8]-1 |r| |
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| Structure | 
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