| Reaction Details |
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 | Report a problem with these data |
| Target | AMP deaminase 3 |
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| Ligand | BDBM50087332 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_31886 (CHEMBL645676) |
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| Ki | 410±n/a nM |
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| Citation |  Kasibhatla, SR; Bookser, BC; Xiao, W; Erion, MD AMP deaminase inhibitors. 5. Design, synthesis, and SAR of a highly potent inhibitor series. J Med Chem44:613-8 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| AMP deaminase 3 |
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| Name: | AMP deaminase 3 |
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| Synonyms: | AMP deaminase 3 | AMP deaminase 3 (hAMPD3) | AMPD3 | AMPD3_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 88818.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 767 |
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| Sequence: | MPRQFPKLNISEVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPIGQKEAKERELQ
KELAEQKSVETAKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTPVVTGATSLP
TPAPYAMPEFQRVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLAYHRFPRITSQY
LGHPRADTAPPEEGLPDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFVYDNKKMLEH
QEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKEL
KSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFD
GLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARM
VKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIF
RSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDK
SPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAF
LTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSL
STDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYY
KEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN
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| BDBM50087332 |
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| n/a |
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| Name | BDBM50087332 |
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| Synonyms: | 2-Benzyl-6-(8-hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-yl)-hexanoic acid | 2-Benzyl-6-(8-hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-yl)-hexanoic acid H2O.0.2CH3CO2H | CHEMBL35929 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24N4O3 |
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| Mol. Mass. | 356.4189 |
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| SMILES | OC1CNC=Nc2c1ncn2CCCCC(Cc1ccccc1)C(O)=O |c:4| |
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| Structure | 
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