| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosinase |
|---|
| Ligand | BDBM50205807 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1980487 (CHEMBL4613749) |
|---|
| IC50 | 1500±n/a nM |
|---|
| Citation |  Alsayari, A; Muhsinah, AB; Hassan, MZ; Ahsan, MJ; Alshehri, JA; Begum, N Aurone: A biologically attractive scaffold as anticancer agent. Eur J Med Chem166:417-431 (2019) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tyrosinase |
|---|
| Name: | Tyrosinase |
|---|
| Synonyms: | LB24-AB | Monophenol monooxygenase | SK29-AB | TYR | TYRO_HUMAN | Tumor rejection antigen AB |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 60388.08 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P14679 |
|---|
| Residue: | 529 |
|---|
| Sequence: | MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILL
SNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVR
RNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMH
YYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRD
AEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRN
PGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQS
SMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGH
NRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLG
AAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHL
|
|
|
|---|
| BDBM50205807 |
|---|
| n/a |
|---|
| Name | BDBM50205807 |
|---|
| Synonyms: | CHEMBL3978212 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H9NO5 |
|---|
| Mol. Mass. | 271.225 |
|---|
| SMILES | Oc1ccc2C(=O)\C(Oc2c1)=C\c1ccc(=O)n(O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
