| Reaction Details |
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 | Report a problem with these data |
| Target | Endothelin receptor type B |
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| Ligand | BDBM50097182 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_63862 |
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| IC50 | 470±n/a nM |
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| Citation |  Dasgupta, F; Gangadhar, N; Bruhaspathy, M; Verma, AK; Sarin, S; Mukherjee, AK Peptoids as endothelin receptor antagonists. Bioorg Med Chem Lett11:555-7 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Endothelin receptor type B |
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| Name: | Endothelin receptor type B |
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| Synonyms: | EDNRB | EDNRB_PIG | Endothelin receptor ET-B |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49616.89 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_63872 |
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| Residue: | 443 |
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| Sequence: | MQPLRSLCGRALVALIFACGVAGVQSEERGFPPAGATPPALRTGEIVAPPTKTFWPRGSN
ASLPRSSSPPQMPKGGRMAGPPARTLTPPPCEGPIEIKDTFKYINTVVSCLVFVLGIIGN
STLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINVYKLLAEDWPFGVEMCKLVPF
IQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEALG
FDMITTDYKGNRLRICLLHPTQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCE
MLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQNDSNRCE
LLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQS
CLKFKANDHGYDNFRSSNKYSSS
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| BDBM50097182 |
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| n/a |
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| Name | BDBM50097182 |
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| Synonyms: | 2-[((E)-3-Benzo[1,3]dioxol-5-yl-acryloyl)-(4-methoxy-benzyl)-amino]-3-(1H-indol-3-yl)-propionic acid | CHEMBL356916 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H26N2O6 |
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| Mol. Mass. | 498.5265 |
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| SMILES | COc1ccc(CN(C(Cc2c[nH]c3ccccc23)C(O)=O)C(=O)\C=C\c2ccc3OCOc3c2)cc1 |
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| Structure | 
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