| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin G/H synthase 2 |
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| Ligand | BDBM50022309 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_217832 (CHEMBL822752) |
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| IC50 | 3790±n/a nM |
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| Citation |  Meinke, PT Perspectives in animal health: old targets and new opportunities. J Med Chem44:641-59 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin G/H synthase 2 |
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| Name: | Prostaglandin G/H synthase 2 |
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| Synonyms: | Cyclooxygenase-2 | Prostaglandin G/H synthase-2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 68982.35 |
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| Organism: | Canis familiaris |
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| Description: | ChEMBL_344386 |
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| Residue: | 604 |
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| Sequence: | MLARALVLCAALAVVRAANPCCSHPCQNQGICMSTGFDQYKCDCTRTGFYGENCSTPEFL
TRIKLYLKPTPNTVHYILTHFKGVWNIVNNIPFLRNTIMKYVLTSRSHLIESPPTYNVNY
GYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGKKELPDSKEIVEKFLLRRKFIPDPQGT
NMMFAFFAQHFTHQFFKTDHKRGPAFTKGLGHGVDLNHVYGETLDRQHKLRLFKDGKMKY
QVIDGEVYPPTVKDTQVEMIYPPHVPEHLQFAVGQEVFGLVPGLMMYATIWLREHNRVCD
VLKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQ
NRIAAEFNTLYHWHPLLPDTLQIDDQEYNFQQFIYNNSILLEHGLTQFVESFSRQIAGRV
AGGRNVPAAVQQVAKASIDQSRQMKYQSLNEYRKRFRLKPYTSFEELTGEKEMAAGLEAL
YGDIDAMELYPALLVEKPRPDAIFGETMVEMGAPFSLKGLMGNPICSPDYWKPSTFGGEV
GFKIINTASIQSLICNNVKGCPFTAFSVQDGQLTKTVTINASSSHSGLDDINPTVLLKER
STEL
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| BDBM50022309 |
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| n/a |
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| Name | BDBM50022309 |
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| Synonyms: | 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine | 4-butyl-1,2-diphenylpyrazolidine-3,5-dione | 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione | CHEMBL101 | PHENYLBUTAZONE | Phenylbutazon |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20N2O2 |
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| Mol. Mass. | 308.3743 |
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| SMILES | CCCCc1c(O)n(-c2ccccc2)n(-c2ccccc2)c1=O |
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| Structure | 
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