| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-glucuronidase |
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| Ligand | BDBM50540964 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1983573 (CHEMBL4616979) |
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| IC50 | 42490±n/a nM |
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| Citation |  Awolade, P; Cele, N; Kerru, N; Gummidi, L; Oluwakemi, E; Singh, P Therapeutic significance of ?-glucuronidase activity and its inhibitors: A review. Eur J Med Chem187:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-glucuronidase |
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| Name: | Beta-glucuronidase |
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| Synonyms: | BGLR_RAT | Gus | Gusb |
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| Type: | PROTEIN |
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| Mol. Mass.: | 74794.72 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_37581 |
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| Residue: | 648 |
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| Sequence: | MSPRRSVCWFVLGQLLCSCAVALQGGMLFPKETPSRELKVLDGLWSFRADYSNNRLQGFE
KQWYRQPLRESGPTLDMPVPSSFNDITQEAELRNFIGWVWYEREAVLPQRWTQDTDRRVV
LRINSAHYYAVVWVNGIHVVEHEGGHLPFEADITKLVQSGPLTTFRVTIAINNTLTPYTL
PPGTIVYKTDPSMYPKGYFVQDISFDFFNYAGLHRSVVLYTTPTTYIDDITVTTDVDRDV
GLVNYWISVQGSDHFQLEVRLLDEDGKIVARGTGNEGQLKVPRAHLWWPYLMHEHPAYLY
SLEVTMTTPESVSDFYTLPVGIRTVAVTKSKFLINGKPFYFQGVNKHEDSDIRGRGFDWP
LLIKDFNLLRWLGANSFRTSHYPYSEEVLQLCDRYGIVVIDECPGVGIVLPQSFGNVSLR
HHLEVMDELVRRDKNHPAVVMWSVANEPVSSLKPAGYYFKTLIAHTKALDPTRPVTFVSN
TRYDADMGAPYVDVICVNSYLSWYHDYGHLEVIQLQLTSQFENWYKMYQKPIIQSEYGAD
AVSGLHEDPPRMFSEEYQTALLENYHLILDEKRKEYVIGELIWNFADFMTNQSPLRVTGN
KKGIFTRQRNPKMAAFILRERYWRIANETRGYGSVPRTQCMGSRPFTF
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| BDBM50540964 |
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| n/a |
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| Name | BDBM50540964 |
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| Synonyms: | CHEMBL4642119 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H46O5 |
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| Mol. Mass. | 486.6832 |
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| SMILES | [H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](O)[C@@](C)(CO)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| |
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| Structure | 
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