| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-chimaerin |
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| Ligand | BDBM50098227 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_39037 (CHEMBL653433) |
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| Ki | 1500±n/a nM |
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| Citation |  Roaten, JB; Kazanietz, MG; Sweatman, TW; Lothstein, L; Israel, M; Parrill, AL Molecular models of N-benzyladriamycin-14-valerate (AD 198) in complex with the phorbol ester-binding C1b domain of protein kinase C-delta. J Med Chem44:1028-34 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-chimaerin |
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| Name: | Beta-chimaerin |
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| Synonyms: | ARHGAP3 | BCH | CHIO_HUMAN | CHN2 | Rho-GTPase-activating protein 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53932.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_39037 |
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| Residue: | 468 |
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| Sequence: | MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF
HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF
ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT
NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA
QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE
IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP
IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN
FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
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| BDBM50098227 |
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| n/a |
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| Name | BDBM50098227 |
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| Synonyms: | CHEMBL275750 | Pentanoic acid 2-[4-(3-benzylamino-4-hydroxy-5-methyl-cyclohexyloxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacen-2-yl]-2-oxo-ethyl ester (AD 198) |
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| Type | Small organic molecule |
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| Emp. Form. | C40H45NO11 |
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| Mol. Mass. | 715.7854 |
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| SMILES | CCCCC(=O)OCC(=O)[C@]1(O)C[C@@H](O[C@@H]2C[C@H](C)[C@H](O)[C@H](C2)NCc2ccccc2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1 |
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| Structure | 
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