| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50541721 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1985283 (CHEMBL4618689) |
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| Ki | 2.1±n/a nM |
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| Citation |  Mugnaini, C; Kostrzewa, M; Bryk, M; Mahmoud, AM; Brizzi, A; Lamponi, S; Giorgi, G; Ferlenghi, F; Vacondio, F; Maccioni, P; Colombo, G; Mor, M; Starowicz, K; Di Marzo, V; Ligresti, A; Corelli, F Design, Synthesis, and Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3- J Med Chem63:7369-7391 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50541721 |
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| n/a |
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| Name | BDBM50541721 |
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| Synonyms: | CHEMBL4633927 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H29FN4O3 |
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| Mol. Mass. | 416.4891 |
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| SMILES | Cn1cc2n(CCCCF)c(=O)c(C(=O)NC34CC5CC(CC(C5)C3)C4)c(O)c2n1 |TLB:19:20:18.17.23:24,THB:19:18:25.20.21:24,21:20:17:23.22.24,21:22:25.20.19:17| |
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| Structure | 
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