| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metallo-beta-lactamase type 2 |
|---|
| Ligand | BDBM50099192 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_48697 |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Sandanayaka, VP; Feigelson, GB; Prashad, AS; Yang, Y; Petersen, PJ Allyl and propargyl substituted penam sulfones as versatile intermediates toward the syntheses of new beta-lactamase inhibitors. Bioorg Med Chem Lett11:997-1000 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Metallo-beta-lactamase type 2 |
|---|
| Name: | Metallo-beta-lactamase type 2 |
|---|
| Synonyms: | BLAB_BACFG | Beta-lactamase type II | ccrA | cfiA |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 27252.87 |
|---|
| Organism: | Bacteroides fragilis |
|---|
| Description: | ChEMBL_1502123 |
|---|
| Residue: | 249 |
|---|
| Sequence: | MKTVFILISMLFPVAVMAQKSVKISDDISITQLSDKVYTYVSLAEIEGWGMVPSNGMIVI
NNHQAALLDTPINDAQTEMLVNWVTDSLHAKVTTFIPNHWHGDCIGGLGYLQRKGVQSYA
NQMTIDLAKEKGLPVPEHGFTDSLTVSLDGMPLQCYYLGGGHATDNIVVWLPTENILFGG
CMLKDNQATSIGNISDADVTAWPKTLDKVKAKFPSARYVVPGHGDYGGTELIEHTKQIVN
QYIESTSKP
|
|
|
|---|
| BDBM50099192 |
|---|
| n/a |
|---|
| Name | BDBM50099192 |
|---|
| Synonyms: | (2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-phenyl-1H-[1,2,3]triazol-4-ylmethyl)-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | CHEMBL6220 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H18N4O5S |
|---|
| Mol. Mass. | 390.414 |
|---|
| SMILES | CC1(C)[C@@H](N2[C@@H]([C@H](Cc3cn(nn3)-c3ccccc3)C2=O)S1(=O)=O)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
