| Reaction Details |
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 | Report a problem with these data |
| Target | Metallo-beta-lactamase type 2 |
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| Ligand | BDBM50099189 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_48697 |
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| IC50 | >100000±n/a nM |
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| Citation |  Sandanayaka, VP; Feigelson, GB; Prashad, AS; Yang, Y; Petersen, PJ Allyl and propargyl substituted penam sulfones as versatile intermediates toward the syntheses of new beta-lactamase inhibitors. Bioorg Med Chem Lett11:997-1000 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Metallo-beta-lactamase type 2 |
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| Name: | Metallo-beta-lactamase type 2 |
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| Synonyms: | BLAB_BACFG | Beta-lactamase type II | ccrA | cfiA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27252.87 |
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| Organism: | Bacteroides fragilis |
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| Description: | ChEMBL_1502123 |
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| Residue: | 249 |
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| Sequence: | MKTVFILISMLFPVAVMAQKSVKISDDISITQLSDKVYTYVSLAEIEGWGMVPSNGMIVI
NNHQAALLDTPINDAQTEMLVNWVTDSLHAKVTTFIPNHWHGDCIGGLGYLQRKGVQSYA
NQMTIDLAKEKGLPVPEHGFTDSLTVSLDGMPLQCYYLGGGHATDNIVVWLPTENILFGG
CMLKDNQATSIGNISDADVTAWPKTLDKVKAKFPSARYVVPGHGDYGGTELIEHTKQIVN
QYIESTSKP
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| BDBM50099189 |
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| n/a |
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| Name | BDBM50099189 |
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| Synonyms: | (2S,5R)-6-((E)-3-Methoxycarbonyl-allyl)-3,3-dimethyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | CHEMBL6309 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H17NO7S |
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| Mol. Mass. | 331.342 |
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| SMILES | COC(=O)\C=C\CC1[C@@H]2N([C@@H](C(O)=O)C(C)(C)S2(=O)=O)C1=O |
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| Structure | 
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