| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide FF receptor 2 |
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| Ligand | BDBM50099303 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_140778 (CHEMBL752767) |
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| Ki | 13600±n/a nM |
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| Citation |  Prokai, L; Prokai-Tatrai, K; Zharikova, A; Li, X; Rocca, JR Combinatorial lead optimization of a neuropeptide FF antagonist. J Med Chem44:1623-6 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide FF receptor 2 |
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| Name: | Neuropeptide FF receptor 2 |
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| Synonyms: | G-protein coupled receptor 74 | Gpr74 | NPFF2_RAT | Neuropeptide G-protein coupled receptor | Npff2 | Npffr2 | Npgpr |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47725.66 |
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| Organism: | RAT |
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| Description: | NPFF2 0 RAT::Q9EQD2 |
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| Residue: | 417 |
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| Sequence: | MGKRWDSNSSGSWDHIWSGNDTQHPWYSDINITYMNYYLHQPHVTAVFISSYFLIFFLCM
VGNTVVCFVVIRNRYMHTVTNFFIFNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKI
SGLVQGISVAASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVMIVIIWGLAITIMTPSAI
MLHVQEEKYYRVRLSSHNKTSTVYWCREDWPNQEMRRIYTTVLFATIYLAPLSLIVIMYA
RIGASLFKTSAHSTGKQRLEQWHVSKKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYAD
LSPNKLRVINIYVYPFAHWLAFCNSSVNPIIYGFFNENFRSGFQDAFQFCQKKVKPQEAY
GLRAKRNLDINTSGLLVHEPASQNPSGENLGCRKSADNPTQESLMEETGEATNSTET
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| BDBM50099303 |
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| n/a |
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| Name | BDBM50099303 |
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| Synonyms: | 2-{[1-(5-Dimethylamino-naphthalene-1-sulfonyl)-pyrrolidine-2-carbonyl]-amino}-pentanedioic acid 5-amide 1-[(1-carbamoyl-4-guanidino-butyl)-amide] | CHEMBL42678 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H41N9O6S |
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| Mol. Mass. | 631.747 |
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| SMILES | CN(C)c1cccc2c(cccc12)S(=O)(=O)N1CCCC1C(=O)NC(CCC(N)=O)C(=O)NC(CCCNC(N)=N)C(N)=O |
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| Structure | 
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