| Reaction Details |
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 | Report a problem with these data |
| Target | Fusion glycoprotein F0 |
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| Ligand | BDBM50542661 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1987321 (CHEMBL4620868) |
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| EC50 | 0.501187±n/a nM |
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| Citation |  Vendeville, S; Tahri, A; Hu, L; Demin, S; Cooymans, L; Vos, A; Kwanten, L; Van den Berg, J; Battles, MB; McLellan, JS; Koul, A; Raboisson, P; Roymans, D; Jonckers, THM Discovery of 3-({5-Chloro-1-[3-(methylsulfonyl)propyl]-1 J Med Chem63:8046-8058 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Fusion glycoprotein F0 |
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| Name: | Fusion glycoprotein F0 |
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| Synonyms: | F | Fusion glycoprotein F0 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63485.30 |
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| Organism: | Human respiratory syncytial virus |
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| Description: | ChEMBL_106144 |
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| Residue: | 574 |
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| Sequence: | MELPILKANAITTILAAVTFCFASSQNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIE
LSNIKENKCNGTDAKVKLMKQELDKYKNAVTELQLLMQSTPAANNRARRELPRFMNYTLN
NTKKTNVTLSKKRKRRFLGFLLGVGSAIASGIAVSKVLHLEGEVNKIKSALLSTNKAVVS
LSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCRISNIETVIEFQQKNNRLLEITREFSVN
AGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEVLAYV
VQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKV
QSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKT
KCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDP
LVFPSDEFDASISQVNEKINQSLAFIRKSDELLHNVNAGKSTTNIMITTIIIVIIVILLS
LIAVGLLLYCKARSTPVTLSKDQLSGINNIAFSN
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| BDBM50542661 |
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| n/a |
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| Name | BDBM50542661 |
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| Synonyms: | CHEMBL4646241 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H20ClN5O3 |
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| Mol. Mass. | 485.922 |
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| SMILES | OC(=O)c1ccc(cc1)-n1c2ccncc2n(Cc2cc3cc(Cl)ccc3n2CCCC#N)c1=O |
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| Structure | 
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