| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histone deacetylase 2b |
|---|
| Ligand | BDBM50422363 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_87387 (CHEMBL881938) |
|---|
| IC50 | 110±n/a nM |
|---|
| Citation |  Massa, S; Mai, A; Sbardella, G; Esposito, M; Ragno, R; Loidl, P; Brosch, G 3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors. J Med Chem44:2069-72 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histone deacetylase 2b |
|---|
| Name: | Histone deacetylase 2b |
|---|
| Synonyms: | Histone deacetylase HD2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 30785.07 |
|---|
| Organism: | Zea mays |
|---|
| Description: | ChEMBL_87549 |
|---|
| Residue: | 286 |
|---|
| Sequence: | MEVGGQEVKPGATVSCKVGDGLVIHLSQAALGESKKASENAILSVNIDDKKLVLGTLSVE
KHPQISCDLVFDKDFELPHNSKTRSVFFRGYKSPVPLFESNSGEDSSDEELKTDQIPLQN
NEIKISAAKVPAKDDDDDVFIILAMMMMIYSSDDDDDDFTTSDSDNEMSEEDDSSDEDEM
SEEDDSSDEDEMSGGADPSDDSSDESGSEHTSAPKKTDVVVGKKRAIKAEAPYGKKAKSE
QSSQKTGDKASTSHPAKQSIKTPADKSRKTPTADKKSPKSGSHGCK
|
|
|
|---|
| BDBM50422363 |
|---|
| n/a |
|---|
| Name | BDBM50422363 |
|---|
| Synonyms: | CHEMBL2311176 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H34N4O6 |
|---|
| Mol. Mass. | 450.5286 |
|---|
| SMILES | C[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCCCCC(=O)[C@@H]2CO2)NC(=O)[C@@H](C)NC1=O |
|---|
| Structure | 
|
|---|
Search and Browse
