| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Interstitial collagenase |
|---|
| Ligand | BDBM50101526 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_106153 (CHEMBL718849) |
|---|
| Ki | 296±n/a nM |
|---|
| Citation |  Terp, GE; Johansen, BN; Christensen, IT; Jørgensen, FS A new concept for multidimensional selection of ligand conformations (MultiSelect) and multidimensional scoring (MultiScore) of protein-ligand binding affinities. J Med Chem44:2333-43 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Interstitial collagenase |
|---|
| Name: | Interstitial collagenase |
|---|
| Synonyms: | CLG | Fibroblast collagenase | MMP1 | MMP1_HUMAN | Matrix metalloproteinase-1 | Matrix metalloproteinase-1 (MMP-1) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 54010.26 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P03956 |
|---|
| Residue: | 469 |
|---|
| Sequence: | MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPV
VEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIEN
YTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGN
LAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSY
TFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDR
FYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGY
PKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFP
GIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKN
|
|
|
|---|
| BDBM50101526 |
|---|
| n/a |
|---|
| Name | BDBM50101526 |
|---|
| Synonyms: | (R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-2-[3-(4-fluoro-phenyl)-propyl]-N*4*-hydroxy-succinamide | CHEMBL308511 | N*1*-(2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-2-[3-(4-fluoro-phenyl)-propyl]-N*4*-hydroxy-succinamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H40FN3O4 |
|---|
| Mol. Mass. | 525.6547 |
|---|
| SMILES | ONC(=O)C[C@@H](CCCc1ccc(F)cc1)C(=O)N[C@@H](CC1CCCCC1)C(=O)NCCc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
