| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 12 |
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| Ligand | BDBM50101893 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_162514 |
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| IC50 | 22000±n/a nM |
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| Citation |  Scarborough, RM; Laibelman, AM; Clizbe, LA; Fretto, LJ; Conley, PB; Reynolds, EE; Sedlock, DM; Jantzen, H Novel tricyclic benzothiazolo[2,3-c]thiadiazine antagonists of the platelet ADP receptor (P2Y(12)). Bioorg Med Chem Lett11:1805-8 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 12 |
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| Name: | P2Y purinoceptor 12 |
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| Synonyms: | ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39458.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9H244 |
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| Residue: | 342 |
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| Sequence: | MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI
IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI
DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS
EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI
IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF
LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
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| BDBM50101893 |
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| n/a |
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| Name | BDBM50101893 |
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| Synonyms: | 2-(4-Hydroxy-7-methyl-2,2-dioxo-2H-2lambda*6*,9-dithia-1,4a-diaza-fluoren-3-yl)-2-oxo-ethanesulfonic acid (6-methyl-benzothiazol-2-yl)-amide | CHEMBL301991 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16N4O6S4 |
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| Mol. Mass. | 536.624 |
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| SMILES | Cc1ccc2N3C(Sc2c1)=NS(=O)(=O)C(C(=O)CS(=O)(=O)Nc1nc2ccc(C)cc2s1)C3=O |c:11| |
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| Structure | 
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