Reaction Details |
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Target | Glutamyl-tRNA(Gln) amidotransferase subunit C |
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Ligand | BDBM50104414 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_72011 (CHEMBL681800) |
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IC50 | >80000±n/a nM |
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Citation | Decicco, CP; Nelson, DJ; Luo, Y; Shen, L; Horiuchi, KY; Amsler, KM; Foster, LA; Spitz, SM; Merrill, JJ; Sizemore, CF; Rogers, KC; Copeland, RA; Harpel, MR Glutamyl-gamma-boronate inhibitors of bacterial Glu-tRNA(Gln) amidotransferase. Bioorg Med Chem Lett11:2561-4 (2001) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Glutamyl-tRNA(Gln) amidotransferase subunit C |
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Name: | Glutamyl-tRNA(Gln) amidotransferase subunit C |
Synonyms: | GATC_STRP1 | gatC |
Type: | PROTEIN |
Mol. Mass.: | 11062.35 |
Organism: | Streptococcus pyogenes serotype M1 |
Description: | ChEMBL_72840 |
Residue: | 100 |
Sequence: | MKISEEEVRHVAKLSKLSFSESETTTFATTLSKIVDMVELLNEVDTEGVAITTTMADKKN
VMRQDVAEEGTDRALLFKNVPEKENHFIKVPAILDDGGDA
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BDBM50104414 |
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n/a |
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Name | BDBM50104414 |
Synonyms: | (S)-2-Benzyloxycarbonylamino-4-((1R,5S)-5,9,9-trimethyl-2,4-dioxa-3-bora-tricyclo[6.1.1.0*1,5*]dec-3-yl)-butyric acid methyl ester | CHEMBL313581 |
Type | Small organic molecule |
Emp. Form. | C23H32BNO6 |
Mol. Mass. | 429.314 |
SMILES | COC(=O)[C@H](CCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C)NC(=O)OCc1ccccc1 |
Structure |
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