Reaction Details |
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Target | Glutamyl-tRNA(Gln) amidotransferase subunit C |
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Ligand | BDBM50104428 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_72011 |
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IC50 | 4700±n/a nM |
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Citation | Decicco, CP; Nelson, DJ; Luo, Y; Shen, L; Horiuchi, KY; Amsler, KM; Foster, LA; Spitz, SM; Merrill, JJ; Sizemore, CF; Rogers, KC; Copeland, RA; Harpel, MR Glutamyl-gamma-boronate inhibitors of bacterial Glu-tRNA(Gln) amidotransferase. Bioorg Med Chem Lett11:2561-4 (2001) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Glutamyl-tRNA(Gln) amidotransferase subunit C |
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Name: | Glutamyl-tRNA(Gln) amidotransferase subunit C |
Synonyms: | GATC_STRP1 | gatC |
Type: | PROTEIN |
Mol. Mass.: | 11062.35 |
Organism: | Streptococcus pyogenes serotype M1 |
Description: | ChEMBL_72840 |
Residue: | 100 |
Sequence: | MKISEEEVRHVAKLSKLSFSESETTTFATTLSKIVDMVELLNEVDTEGVAITTTMADKKN
VMRQDVAEEGTDRALLFKNVPEKENHFIKVPAILDDGGDA
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BDBM50104428 |
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n/a |
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Name | BDBM50104428 |
Synonyms: | CHEMBL83018 | N-[(S)-2-Amino-4-((1R,5S)-5,9,9-trimethyl-2,4-dioxa-3-bora-tricyclo[6.1.1.0*1,5*]dec-3-yl)-butyryl]-C,C,C-trifluoro-methanesulfonamide |
Type | Small organic molecule |
Emp. Form. | C15H24BF3N2O5S |
Mol. Mass. | 412.233 |
SMILES | CC1(C)C2C[C@@]11OB(CC[C@H](N)C(=O)NS(=O)(=O)C(F)(F)F)O[C@@]1(C)CC2 |
Structure |
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