| Reaction Details |
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 | Report a problem with these data |
| Target | C3a anaphylatoxin chemotactic receptor |
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| Ligand | BDBM50105654 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_41309 |
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| IC50 | 11410±n/a nM |
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| Citation |  Grant, EB; Guiadeen, D; Singer, M; Argentieri, D; Hlasta, DJ; Wachter, M Design, synthesis, and biological activity of diiminoisoindolines as complement component 3a antagonists. Bioorg Med Chem Lett11:2817-20 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| C3a anaphylatoxin chemotactic receptor |
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| Name: | C3a anaphylatoxin chemotactic receptor |
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| Synonyms: | AZ3B | C3AR | C3AR1 | C3AR_HUMAN | C3R1 | C3a-R | HNFAG09 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53864.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_642034 |
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| Residue: | 482 |
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| Sequence: | MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIW
FLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDR
CLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSS
SLDYPDFYGDPLENRSLENIVQPPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSAD
SLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSA
SSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIV
FRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVC
IALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERNST
TV
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| BDBM50105654 |
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| n/a |
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| Name | BDBM50105654 |
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| Synonyms: | 1,3-Bis-[(Z)-2-(4-fluoro-phenyl)-ethylimino]-2,3-dihydro-1H-isoindole | CHEMBL97303 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H21F2N3 |
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| Mol. Mass. | 389.4404 |
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| SMILES | Fc1ccc(CCNC2=N\C(=N/CCc3ccc(F)cc3)c3ccccc23)cc1 |t:8| |
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| Structure | 
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