| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 84 |
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| Ligand | BDBM50548385 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2022089 (CHEMBL4675902) |
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| IC50 | 54±n/a nM |
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| Citation |  Labéguère, F; Dupont, S; Alvey, L; Soulas, F; Newsome, G; Tirera, A; Quenehen, V; Mai, TTT; Deprez, P; Blanqué, R; Oste, L; Le Tallec, S; De Vos, S; Hagers, A; Vandevelde, A; Nelles, L; Vandervoort, N; Conrath, K; Christophe, T; van der Aar, E; Wakselman, E; Merciris, D; Cottereaux, C; da Costa, C; Saniere, L; Clement-Lacroix, P; Jenkins, L; Milligan, G; Fletcher, S; Brys, R; Gosmini, R Discovery of 9-Cyclopropylethynyl-2-(( J Med Chem63:13526-13545 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 84 |
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| Name: | G-protein coupled receptor 84 |
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| Synonyms: | EX33 | G-protein coupled receptor 84 | GPR84 | GPR84_HUMAN | Inflammation-related G-protein coupled receptor EX33 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43726.73 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_116040 |
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| Residue: | 396 |
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| Sequence: | MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIA
NLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYL
LIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTT
ILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQE
LDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQP
IKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTW
LNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
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| BDBM50548385 |
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| n/a |
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| Name | BDBM50548385 |
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| Synonyms: | Glpg-1205 | Glpg1205 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22N2O4 |
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| Mol. Mass. | 378.4211 |
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| SMILES | O=c1nc(OC[C@@H]2COCCO2)cc2-c3ccc(cc3CCn12)C#CC1CC1 |r| |
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| Structure | 
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