| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50548580 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2022616 (CHEMBL4676429) |
|---|
| Ki | 156±n/a nM |
|---|
| Citation |  García, M; Virgili, M; Alonso, M; Alegret, C; Farran, J; Fernández, B; Bordas, M; Pascual, R; Burgueño, J; Vidal-Torres, A; Fernández de Henestrosa, AR; Ayet, E; Merlos, M; Vela, JM; Plata-Salamán, CR; Almansa, C Discovery of EST73502, a Dual ?-Opioid Receptor Agonist and ? J Med Chem63:15508-15526 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44789.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35372 |
|---|
| Residue: | 400 |
|---|
| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
|
|
|
|---|
| BDBM50548580 |
|---|
| n/a |
|---|
| Name | BDBM50548580 |
|---|
| Synonyms: | CHEMBL4786209 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H26N2O2 |
|---|
| Mol. Mass. | 302.4112 |
|---|
| SMILES | CC1OC2(CCN(CCc3ccccc3)CC2)CN(C)C1=O |
|---|
| Structure | 
|
|---|
Search and Browse
