| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gastrin/cholecystokinin type B receptor |
|---|
| Ligand | BDBM50549228 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2024092 (CHEMBL4677905) |
|---|
| EC50 | 1.3±n/a nM |
|---|
| Citation |  Klingler, M; Hörmann, AA; Rangger, C; Desrues, L; Castel, H; Gandolfo, P; von Guggenberg, E Stabilization Strategies for Linear Minigastrin Analogues: Further Improvements J Med Chem63:14668-14679 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Gastrin/cholecystokinin type B receptor |
|---|
| Name: | Gastrin/cholecystokinin type B receptor |
|---|
| Synonyms: | Cckbr | Cholecystokinin A | Cholecystokinin B receptor | Cholecystokinin receptor | GASR_RAT | Gastrin/cholecystokinin type B receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 48980.43 |
|---|
| Organism: | RAT |
|---|
| Description: | Cholecystokinin A CCKBR RAT::P30553 |
|---|
| Residue: | 452 |
|---|
| Sequence: | MELLKLNRSVQGPGPGSGSSLCRPGVSLLNSSSAGNLSCDPPRIRGTGTRELEMAIRITL
YAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
IFGTVICKAISYLMGVSVSVSTLNLVAIALERYSAICRPLQARVWQTRSHAARVILATWL
LSGLLMVPYPVYTMVQPVGPRVLQCMHRWPSARVQQTWSVLLLLLLFFIPGVVIAVAYGL
ISRELYLGLHFDGENDSETQSRARNQGGLPGGAAPGPVHQNGGCRPVTSVAGEDSDGCCV
QLPRSRLEMTTLTTPTPGPVPGPRPNQAKLLAKKRVVRMLLVIVLLFFLCWLPVYSVNTW
RAFDGPGAQRALSGAPISFIHLLSYVSACVNPLVYCFMHRRFRQACLDTCARCCPRPPRA
RPQPLPDEDPPTPSIASLSRLSYTTISTLGPG
|
|
|
|---|
| BDBM50549228 |
|---|
| n/a |
|---|
| Name | BDBM50549228 |
|---|
| Synonyms: | CHEMBL4758706 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C73H96N14O20 |
|---|
| Mol. Mass. | 1489.6251 |
|---|
| SMILES | CCCC[C@H](N(C)C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@@H](CCC(O)=O)NC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1cccc2ccccc12)C(N)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
