| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glycine receptor subunit alpha-4 |
|---|
| Ligand | BDBM50108654 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_70971 (CHEMBL857373) |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Maier, CA; Wünsch, B Novel spiropiperidines as highly potent and subtype selective sigma-receptor ligands. Part 1. J Med Chem45:438-48 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glycine receptor subunit alpha-4 |
|---|
| Name: | Glycine receptor subunit alpha-4 |
|---|
| Synonyms: | GLRA4_MOUSE | Glra4 | Glycine receptor alpha-4 chain |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 52521.54 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_70971 |
|---|
| Residue: | 456 |
|---|
| Sequence: | MTTLVPASLFLLLWTLPGKVLLSVALAKEDVKSGLKGSQPMSPSDFLDKLMGRTSGYDAR
IRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNVFLRQQWNDPRLAYREYPDDSLDLDP
SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNFPM
DIQTCTMQLESFGYTMNDLMFEWLEDAPAVQVAEGLTLPQFILRDEKDLGYCTKHYNTGK
FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQ
SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFMRLRRRQRRQRM
EEDIIRESRFYFRGYGLGHCLQARDGGPMEGSSIYSPQPPTPLLKEGETMRKLYVDRAKR
IDTISRAVFPFTFLVFNIFYWVVYKVLRSEDIHQAL
|
|
|
|---|
| BDBM50108654 |
|---|
| n/a |
|---|
| Name | BDBM50108654 |
|---|
| Synonyms: | 1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-(hexahydropyridine)]-1-yl]-3-phenylpropane | CHEMBL138458 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H29NO2 |
|---|
| Mol. Mass. | 351.4819 |
|---|
| SMILES | COC1Cc2ccccc2C2(CCN(CCCc3ccccc3)CC2)O1 |
|---|
| Structure | 
|
|---|
Search and Browse
