| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50108653 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_58981 (CHEMBL668646) |
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| IC50 | >10000±n/a nM |
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| Citation |  Maier, CA; Wünsch, B Novel spiropiperidines as highly potent and subtype selective sigma-receptor ligands. Part 1. J Med Chem45:438-48 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | D(1A) dopamine receptor | DOPAMINE D1 | DRD1_MOUSE | Dopamine D1 receptor | Dopamine receptor | Drd1 | Drd1a | Gpcr15 |
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| Type: | Enzyme |
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| Mol. Mass.: | 49613.93 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | Q61616 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDETGLPVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
AEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTTGNGNPVECSQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVMFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKREEAGGIPKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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| BDBM50108653 |
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| n/a |
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| Name | BDBM50108653 |
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| Synonyms: | 1'-benzyl-3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-(hexahydropyridine)] | 1'-benzyl-3-methoxyspiro[isochroman-1,4'-piperidine] | CHEMBL141209 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25NO2 |
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| Mol. Mass. | 323.4287 |
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| SMILES | COC1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1 |
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| Structure | 
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