| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50550066 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2026352 (CHEMBL4680510) |
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| EC50 | 0.017000±n/a nM |
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| Citation |  Gutman, ES; Bow, E; Li, F; Sulima, A; Kaska, S; Crowley, R; Prisinzano, TE; Lee, YS; Hassan, SA; Imler, GH; Deschamps, JR; Jacobson, AE; Rice, KC G-Protein biased opioid agonists: 3-hydroxy- RSC Med Chem11:896-904 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50550066 |
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| n/a |
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| Name | BDBM50550066 |
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| Synonyms: | CHEMBL4798954 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27NO2 |
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| Mol. Mass. | 337.4553 |
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| SMILES | [H][C@]12CCC[C@@](CCN1CCc1ccccc1)([C@@H]2O)c1cccc(O)c1 |r,THB:9:8:4.3.2:17| |
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| Structure | 
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