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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | RAS guanyl-releasing protein 1 | ||
| Ligand | BDBM50057511 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_163499 (CHEMBL772411) | ||
| Ki | 2.54±n/a nM | ||
| Citation |  Rong, SB; Enyedy, IJ; Qiao, L; Zhao, L; Ma, D; Pearce, LL; Lorenzo, PS; Stone, JC; Blumberg, PM; Wang, S; Kozikowski, AP Structural basis of RasGRP binding to high-affinity PKC ligands. J Med Chem45:853-60 (2002) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| RAS guanyl-releasing protein 1 | |||
| Name: | RAS guanyl-releasing protein 1 | ||
| Synonyms: | GRP1_RAT | RAS guanyl releasing protein 1 | Rasgrp | Rasgrp1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 90263.87 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_163499 | ||
| Residue: | 795 | ||
| Sequence: |
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| BDBM50057511 | |||
| n/a | |||
| Name | BDBM50057511 | ||
| Synonyms: | (+/-)-indolactum-V 13-Hydroxymethyl-10-isopropyl-9-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-1,4,6,8(15)-tetraen-11-one | (-)-indolactam V | (10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-1,4(15),5,7-tetraen-11-one | (10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-1,4,6,8(15)-tetraen-11-one | (2S,5S)-5-(hydroxymethyl)-2-isopropyl-1-methyl-1,2,5,6-tetrahydro-4H-[1,4]diazonino[7,6,5-cd]indol-3(8H)-one | (S)-13-Hydroxymethyl-10-isopropyl-9-(S)-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-1,4,6,8(15)-tetraen-11-one | 13-Hydroxymethyl-10-isopropyl-9-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-1,4(15),5,7-tetraen-11-one | 13-Hydroxymethyl-10-isopropyl-9-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-1,4,6,8(15)-tetraen-11-one(ILV) | CHEMBL27266 | INDOLACTUM | indolactam-V | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H23N3O2 | ||
| Mol. Mass. | 301.3834 | ||
| SMILES | CC(C)[C@@H]1N(C)c2cccc3[nH]cc(C[C@@H](CO)NC1=O)c23 | ||
| Structure | 
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