| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50110016 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_210649 |
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| Ki | 4.8±n/a nM |
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| Citation |  Künzel, S; Schweinitz, A; Reissmann, S; Stürzebecher, J; Steinmetzer, T 4-amidinobenzylamine-based inhibitors of urokinase. Bioorg Med Chem Lett12:645-8 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM50110016 |
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| n/a |
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| Name | BDBM50110016 |
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| Synonyms: | CHEMBL433510 | Carbonic acid 2-[1-(4-carbamimidoyl-benzylcarbamoyl)-ethylcarbamoyl]-2-phenylmethanesulfonylamino-ethyl ester isobutyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C26H35N5O7S |
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| Mol. Mass. | 561.65 |
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| SMILES | CC(C)COC(=O)OC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)N[C@@H](C)C(=O)NCc1ccc(cc1)C(N)=N |
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| Structure | 
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