| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50550832 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2028587 (CHEMBL4682745) |
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| Ki | 0.086700±n/a nM |
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| Citation |  Abdelrahman, A; Yerande, SG; Namasivayam, V; Klapschinski, TA; Alnouri, MW; El-Tayeb, A; Müller, CE Substituted 4-phenylthiazoles: Development of potent and selective A Eur J Med Chem186:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50550832 |
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| n/a |
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| Name | BDBM50550832 |
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| Synonyms: | CHEMBL4764086 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H15ClN2O2S |
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| Mol. Mass. | 418.895 |
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| SMILES | Clc1ccc(cc1)C(=O)c1sc(NC(=O)c2ccccc2)nc1-c1ccccc1 |
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| Structure | 
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