| Reaction Details |
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 | Report a problem with these data |
| Target | Tissue alpha-L-fucosidase |
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| Ligand | BDBM92460 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2029541 (CHEMBL4683699) |
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| IC50 | 82000±n/a nM |
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| Citation |  Luthra, T; Banothu, V; Adepally, U; Kumar, K; M, S; Chakrabarti, S; Maddi, SR; Sen, S Discovery of novel pyrido-pyrrolidine hybrid compounds as alpha-glucosidase inhibitors and alternative agent for control of type 1 diabetes. Eur J Med Chem188:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tissue alpha-L-fucosidase |
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| Name: | Tissue alpha-L-fucosidase |
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| Synonyms: | Alpha-L-fucosidase 1 | FUCA1 | FUCO_BOVIN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54093.12 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_335897 |
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| Residue: | 468 |
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| Sequence: | MRSWVVGARLLLLLQLVLVLGAVRLPPCTDPRHCTDPPRYTPDWPSLDSRPLPAWFDEAK
FGVFVHWGVFSVPAWGSEWFWWHWQGEKLPQYESFMKENYPPDFSYADFGPRFTARFFNP
DSWADLFKAAGAKYVVLTTKHHEGYTNWPSPVSWNWNSKDVGPHRDLVGELGTAIRKRNI
RYGLYHSLLEWFHPLYLRDKKNGFKTQYFVNAKTMPELYDLVNRYKPDLIWSDGEWECPD
TYWNSTDFLAWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCKDKFQPETLPDHKWEMCT
SIDQRSWGYRRDMEMADITNESTIISELVQTVSLGGNYLLNVGPTKDGLIVPIFQERLLA
VGKWLSINGEAIYASKPWRVQSEKNSVWYTSKGLAVYAILLHWPEYGILSLISPIATSTT
KVTMLGIQKDLKWSLNPSGKGLLVFLPQLPPAALPTEFAWTIKLTGVK
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| BDBM92460 |
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| n/a |
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| Name | BDBM92460 |
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| Synonyms: | Casuarine |
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| Type | Small organic molecule |
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| Emp. Form. | C8H15NO5 |
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| Mol. Mass. | 205.2084 |
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| SMILES | OC[C@@H]1[C@@H](O)[C@H](O)[C@H]2[C@H](O)[C@@H](O)CN12 |
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| Structure | 
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