| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin G/H synthase 2 |
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| Ligand | BDBM50088679 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157994 (CHEMBL766667) |
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| IC50 | <1±n/a nM |
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| Citation |  Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y Thalidomide and its analogues as cyclooxygenase inhibitors. Bioorg Med Chem Lett12:1043-6 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin G/H synthase 2 |
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| Name: | Prostaglandin G/H synthase 2 |
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| Synonyms: | COX2 | Cyclooxygenase-1 (COX-1) | Cyclooxygenase-2 (COX-2) | PGH2_SHEEP | PTGS2 | Prostaglandin G/H synthase (Cyclooxygenase-2) | Prostaglandin G/H synthase (cyclooxygenase) |
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| Type: | Protein |
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| Mol. Mass.: | 68976.98 |
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| Organism: | Ovis aries (Sheep) |
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| Description: | n/a |
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| Residue: | 603 |
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| Sequence: | MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLT
RIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYS
YKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTN
LMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQ
MINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDV
LKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQN
RIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVA
GRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALY
GDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVG
FKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERS
TEL
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| BDBM50088679 |
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| n/a |
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| Name | BDBM50088679 |
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| Synonyms: | 2-Phenyl-isoindole-1,3-dione | 2-phenyl-1H-isoindole-1,3(2H)-dione | 2-phenylisoindoline-1,3-dione | CHEMBL9020 | N-Phenylphtalimide |
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| Type | Small organic molecule |
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| Emp. Form. | C14H9NO2 |
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| Mol. Mass. | 223.2268 |
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| SMILES | O=C1N(C(=O)c2ccccc12)c1ccccc1 |
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| Structure | 
|
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