| Reaction Details |
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 | Report a problem with these data |
| Target | Monoglyceride lipase |
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| Ligand | BDBM50552713 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2035356 (CHEMBL4689514) |
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| IC50 | 0.070000±n/a nM |
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| Citation |  Sabnis, RW Novel Oxazine Monoacylglycerol Lipase (MAGL) Inhibitors. ACS Med Chem Lett12:312-313 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Monoglyceride lipase |
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| Name: | Monoglyceride lipase |
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| Synonyms: | HU-K5 | Lysophospholipase homolog | Lysophospholipase-like | MAGL | MGL | MGLL | MGLL_HUMAN |
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| Type: | Hydrolase |
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| Mol. Mass.: | 33264.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human recombinant MGL (Cayman Chemical, cat# 10008354). |
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| Residue: | 303 |
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| Sequence: | MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE
LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG
HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID
SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR
LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA
SPP
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| BDBM50552713 |
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| n/a |
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| Name | BDBM50552713 |
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| Synonyms: | CHEMBL4745872 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H31N3O3 |
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| Mol. Mass. | 385.4998 |
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| SMILES | [H][C@@]12CN(CC[C@]1([H])OCC(=O)N2)C(=O)N1CC(C1)c1ccc(CC(C)(C)C)cc1 |r| |
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| Structure | 
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