| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-synuclein |
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| Ligand | BDBM15579 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2045854 (CHEMBL4700553) |
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| IC50 | 270±n/a nM |
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| Citation |  Oliveri, V Toward the discovery and development of effective modulators of ?-synuclein amyloid aggregation. Eur J Med Chem167:10-36 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Alpha-synuclein |
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| Name: | Alpha-synuclein |
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| Synonyms: | NACP | PARK1 | SNCA | SYUA_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 14451.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37840 |
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| Residue: | 140 |
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| Sequence: | MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
|
|
|
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| BDBM15579 |
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| n/a |
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| Name | BDBM15579 |
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| Synonyms: | CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-amine | SLG | Selegiline | US8633208, Deprenyl | US9469653, Selegiline | methyl[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-ylamine |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C13H17N |
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| Mol. Mass. | 187.2808 |
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| SMILES | C[C@H](Cc1ccccc1)N(C)CC#C |r| |
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| Structure | 
|
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