Reaction Details |
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Target | Alpha-synuclein |
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Ligand | BDBM50553260 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_2045872 (CHEMBL4700571) |
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Kd | 190±n/a nM |
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Citation | Oliveri, V Toward the discovery and development of effective modulators of ?-synuclein amyloid aggregation. Eur J Med Chem167:10-36 (2019) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Alpha-synuclein |
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Name: | Alpha-synuclein |
Synonyms: | NACP | PARK1 | SNCA | SYUA_HUMAN |
Type: | Protein |
Mol. Mass.: | 14451.42 |
Organism: | Homo sapiens (Human) |
Description: | P37840 |
Residue: | 140 |
Sequence: | MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
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BDBM50553260 |
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n/a |
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Name | BDBM50553260 |
Synonyms: | CHEMBL4748063 |
Type | Small organic molecule |
Emp. Form. | C16H11BrN2O2 |
Mol. Mass. | 343.175 |
SMILES | Brc1cccc(c1)-c1cc([nH]n1)-c1ccc2OCOc2c1 |
Structure |
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