| Reaction Details |
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 | Report a problem with these data |
| Target | Macrophage migration inhibitory factor |
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| Ligand | BDBM50186426 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2047522 (CHEMBL4702221) |
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| Kd | 47000±n/a nM |
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| Citation |  Xiao, Z; Chen, D; Song, S; van der Vlag, R; van der Wouden, PE; van Merkerk, R; Cool, RH; Hirsch, AKH; Melgert, BN; Quax, WJ; Poelarends, GJ; Dekker, FJ 7-Hydroxycoumarins Are Affinity-Based Fluorescent Probes for Competitive Binding Studies of Macrophage Migration Inhibitory Factor. J Med Chem63:11920-11933 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Macrophage migration inhibitory factor |
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| Name: | Macrophage migration inhibitory factor |
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| Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
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| Type: | Enzyme |
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| Mol. Mass.: | 12478.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14174 |
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| Residue: | 115 |
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| Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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| BDBM50186426 |
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| n/a |
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| Name | BDBM50186426 |
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| Synonyms: | CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO-1 | US8618147, ISO-1 | methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate |
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| Type | Small organic molecule |
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| Emp. Form. | C12H13NO4 |
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| Mol. Mass. | 235.2359 |
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| SMILES | COC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:7| |
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| Structure | 
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