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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50114978 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_144132 | ||
| Ki | 17±n/a nM | ||
| Citation |  Islam, I; Dhanoa, D; Finn, J; Du, P; Walker, MW; Salon, JA; Zhang, J; Gluchowski, C Discovery of potent and selective small molecule NPY Y5 receptor antagonists. Bioorg Med Chem Lett12:1767-9 (2002) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50114978 | |||
| n/a | |||
| Name | BDBM50114978 | ||
| Synonyms: | CHEMBL299295 | Naphthalene-1-sulfonic acid (4-{[2-(4-chloro-phenyl)-1-hydroxymethyl-ethylamino]-methyl}-cyclohexylmethyl)-amide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H33ClN2O3S | ||
| Mol. Mass. | 501.081 | ||
| SMILES | OCC(Cc1ccc(Cl)cc1)NC[C@H]1CC[C@H](CNS(=O)(=O)c2cccc3ccccc23)CC1 |wU:16.17,wD:13.13,(6.46,-5.19,;7.82,-4.42,;7.79,-2.88,;9.15,-2.1,;10.48,-2.88,;11.82,-2.1,;13.15,-2.86,;13.15,-4.42,;14.48,-5.19,;11.82,-5.19,;10.48,-4.42,;6.46,-2.1,;5.13,-2.88,;3.8,-2.11,;3.8,-.57,;2.46,.2,;1.13,-.58,;-.2,.19,;-1.54,-.58,;-2.89,.18,;-2.96,-1.27,;-2.89,1.72,;-4.22,-.61,;-4.22,-2.15,;-5.56,-2.92,;-6.89,-2.16,;-6.89,-.61,;-8.22,.14,;-8.22,1.68,;-6.89,2.46,;-5.56,1.7,;-5.56,.16,;1.13,-2.13,;2.46,-2.88,)| | ||
| Structure | 
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