| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 2b |
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| Ligand | BDBM50115653 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_87850 (CHEMBL701990) |
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| IC50 | 40±n/a nM |
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| Citation |  Wittich, S; Scherf, H; Xie, C; Brosch, G; Loidl, P; Gerhäuser, C; Jung, M Structure-activity relationships on phenylalanine-containing inhibitors of histone deacetylase: in vitro enzyme inhibition, induction of differentiation, and inhibition of proliferation in Friend leukemic cells. J Med Chem45:3296-309 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 2b |
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| Name: | Histone deacetylase 2b |
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| Synonyms: | Histone deacetylase HD2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30785.07 |
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| Organism: | Zea mays |
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| Description: | ChEMBL_87549 |
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| Residue: | 286 |
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| Sequence: | MEVGGQEVKPGATVSCKVGDGLVIHLSQAALGESKKASENAILSVNIDDKKLVLGTLSVE
KHPQISCDLVFDKDFELPHNSKTRSVFFRGYKSPVPLFESNSGEDSSDEELKTDQIPLQN
NEIKISAAKVPAKDDDDDVFIILAMMMMIYSSDDDDDDFTTSDSDNEMSEEDDSSDEDEM
SEEDDSSDEDEMSGGADPSDDSSDESGSEHTSAPKKTDVVVGKKRAIKAEAPYGKKAKSE
QSSQKTGDKASTSHPAKQSIKTPADKSRKTPTADKKSPKSGSHGCK
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| BDBM50115653 |
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| n/a |
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| Name | BDBM50115653 |
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| Synonyms: | CHEMBL113095 | Octanedioic acid ((S)-1-benzylcarbamoyl-2-phenyl-ethyl)-amide hydroxyamide | Octanedioic acid (1-benzylcarbamoyl-2-phenyl-ethyl)-amide hydroxyamide |
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| Type | Small organic molecule |
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| Emp. Form. | C24H31N3O4 |
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| Mol. Mass. | 425.5206 |
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| SMILES | ONC(=O)CCCCCCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1ccccc1 |
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| Structure | 
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