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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Corticotropin-releasing factor receptor 1 | ||
| Ligand | BDBM50116119 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_51124 | ||
| Ki | 765±n/a nM | ||
| Citation |  Yuan, J; Gulianello, M; De Lombaert, S; Brodbeck, R; Kieltyka, A; Hodgetts, KJ 3-Aryl pyrazolo[4,3-d]pyrimidine derivatives: Nonpeptide CRF-1 antagonists. Bioorg Med Chem Lett12:2133-6 (2002) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Corticotropin-releasing factor receptor 1 | |||
| Name: | Corticotropin-releasing factor receptor 1 | ||
| Synonyms: | CRF-R | CRF-R2 Alpha | CRF1 | CRFR | CRFR1 | CRFR1_HUMAN | CRH-R 1 | CRHR | CRHR1 | Corticotropin releasing factor receptor 1 | Corticotropin-releasing factor receptor 1 (CRF-1) | Corticotropin-releasing factor receptor 1 (CRF1) | Corticotropin-releasing hormone receptor 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50744.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34998 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM50116119 | |||
| n/a | |||
| Name | BDBM50116119 | ||
| Synonyms: | CHEMBL67360 | [3-(2-Chloro-phenyl)-2,5-dimethyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl]-dipropyl-amine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H24ClN5 | ||
| Mol. Mass. | 357.88 | ||
| SMILES | CCCN(CCC)c1nc(C)nc2c(-c3ccccc3Cl)n(C)nc12 |(1.06,4.4,;-.27,3.63,;-.27,2.09,;-1.6,1.32,;-2.93,2.07,;-2.94,3.61,;-4.28,4.38,;-1.6,-.22,;-2.93,-1,;-2.93,-2.54,;-4.26,-3.31,;-1.6,-3.31,;-.26,-2.54,;1.21,-3.01,;1.69,-4.48,;.66,-5.61,;1.13,-7.08,;2.64,-7.39,;3.67,-6.24,;3.19,-4.78,;4.2,-3.64,;2.13,-1.76,;3.67,-1.76,;1.21,-.51,;-.26,-.99,)| | ||
| Structure | 
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