| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-galactosidase |
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| Ligand | BDBM50220500 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_39372 (CHEMBL653247) |
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| IC50 | 250000±n/a nM |
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| Citation |  Moreno-Vargas, AJ; Demange, R; Fuentes, J; Robina, I; Vogel, P Synthesis of [(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]-5-methylfuran-4-carboxylic acid derivatives: new leads as selective beta-galactosidase inhibitors. Bioorg Med Chem Lett12:2335-9 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-galactosidase |
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| Name: | Beta-galactosidase |
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| Synonyms: | BGAL_ASPNG | lacA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 109138.60 |
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| Organism: | Aspergillus niger |
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| Description: | ChEMBL_39387 |
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| Residue: | 1006 |
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| Sequence: | MKLSSACAIALLAAQAAGASIKHRINGFTLTEHSDPAKRELLQKYVTWDDKSLFINGERI
MIFSGEFHPFRLPVKELQLDIFQKVKALGFNCVSFYVDWALVEGKPGEYRADGIFDLEPF
FDAASEAGIYLLARPGPYINAESSGGGFPGWLQRVNGTLRSSDKAYLDATDNYVSHVAAT
IAKYQITNGGPIILYQPENEYTSGCSGVEFPDPVYMQYVEDQARNAGVVIPLINNDASAS
GNNAPGTGKGAVDIYGHDSYPLGFDCANPTVWPSGDLPTNFRTLHLEQSPTTPYAIVEFQ
GGSYDPWGGPGFAACSELLNNEFERVFYKNDFSFQIAIMNLYMIFGGTNWGNLGYPNGYT
SYDYGSAVTESRNITREKYSELKLLGNFAKVSPGYLTASPGNLTTSGYADTTDLTVTPLL
GNSTGSFFVVRHSDYSSEESTSYKLRLPTSAGSVTIPQLGGTLTLNGRDSKIHVTDHNVS
GTNIIYSTAEVFTWKKFADGKVLVLYGGAGEHHELAISTKSNVTVIEGSESGISSKQTSS
SVVVGWDVSTTRRIIQVGDLKILLLDRNSAYNYWVPQLATDGTSPGFSTPEKVASSIIVK
AGYLVRTAYLKGSGLYLTADFNATTSVEVIGVPSTAKNLFINGDKTSHTVDKNGIWSATV
DYNAPDISLPSLKDLDWKYVDTLPEIQSSYDDSLWPAADLKQTKNTLRSLTTPTSLYSSD
YGFHTGYLLYRGHFTATGNESTFAIDTQGGSAFGSSVWLNGTYLGSWTGLYANSDYNATY
NLPQLQAGKTYVITVVIDNMGLEENWTVGEDLMKSPRGISTSCLPDGQAAPISWKLTGNL
GGEDYEDKVRGPLNEGGLYAERQGFHQPEPPSQNWKSSSPLEGLSEAGIGFYSASFDLDL
PKDGMSHCSSTSVTALRHPRTACRSTSTDIVCEIHKQHRTSDQLPCPRGNPELSRNELVG
GDPVALDSAGGKLESLELSYTTPVLTALGEVESVDQPKYKKRKGAY
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| BDBM50220500 |
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| n/a |
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| Name | BDBM50220500 |
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| Synonyms: | CHEMBL3350286 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H20N2O4 |
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| Mol. Mass. | 268.3089 |
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| SMILES | CC(C)NC(=O)c1cc(oc1C)[C@H]1NC[C@@H](O)[C@H]1O |r| |
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| Structure | 
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