| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-galactosidase |
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| Ligand | BDBM50403936 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_39390 (CHEMBL659248) |
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| IC50 | 12000±n/a nM |
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| Citation |  Moreno-Vargas, AJ; Demange, R; Fuentes, J; Robina, I; Vogel, P Synthesis of [(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]-5-methylfuran-4-carboxylic acid derivatives: new leads as selective beta-galactosidase inhibitors. Bioorg Med Chem Lett12:2335-9 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-galactosidase |
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| Name: | Beta-galactosidase |
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| Synonyms: | Acid beta-galactosidase | BGAL_HUMAN | ELNR1 | Elastin receptor 1 | GLB1 | Lactase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 76074.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_215886 |
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| Residue: | 677 |
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| Sequence: | MPGFLVRILPLLLVLLLLGPTRGLRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRV
PRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVIL
RPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPV
ITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTV
DFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARG
ASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKV
PEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRT
TLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENM
GRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWA
HNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLT
LFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKR
LMPPPPQKNKDSWLDHV
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| BDBM50403936 |
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| n/a |
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| Name | BDBM50403936 |
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| Synonyms: | CHEMBL2114148 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H17NO5 |
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| Mol. Mass. | 255.2671 |
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| SMILES | CCOC(=O)c1cc(oc1C)[C@H]1NC[C@@H](O)[C@H]1O |r| |
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| Structure | 
|
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