| Reaction Details |
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 | Report a problem with these data |
| Target | Protein lifeguard 1 |
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| Ligand | BDBM50118479 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_140550 (CHEMBL747256) |
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| IC50 | 287000.0±n/a nM |
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| Citation |  Clausen, RP; Bräuner-Osborne, H; Greenwood, JR; Hermit, MB; Stensbøl, TB; Nielsen, B; Krogsgaard-Larsen, P Selective agonists at group II metabotropic glutamate receptors: synthesis, stereochemistry, and molecular pharmacology of (S)- and (R)-2-amino-4-(4-hydroxy[1,2,5]thiadiazol-3-yl)butyric acid. J Med Chem45:4240-5 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein lifeguard 1 |
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| Name: | Protein lifeguard 1 |
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| Synonyms: | Glutamate [NMDA] receptor associated protein 1 | Grina | LFG1_RAT | Lfg1 | Nmdara1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38593.19 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_140550 |
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| Residue: | 348 |
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| Sequence: | MSHEKSFLVSGDSYPPPNPGYPVGPQAPMPPYVQPPYPGAPYPQAAFQPSPYGQPGYPHG
PGPYPQGGYPQGPYPQGGYPQGPYPQSPFPPNPYGQPPPFQDPGSPQHGNYQEEGPPSYY
DNQDFPSVNWDKSIRQAFIRKVFLVLTLQLSVTLSTVAIFTFVGEVKGFVRANVWTYYVS
YAIFFISLIVLSCCGDFRRKHPWNLVALSILTISLSYMVGMIASFYNTEAVIMAVGITTA
VCFTVVIFSMQTRYDFTSCMGVLLVSVVVLFIFAILCIFIRNRILEIVYASLGALLFTCF
LAVDTQLLLGNKQLSLSPEEYVFAALNLYTDIINIFLYILTIIGRAKE
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| BDBM50118479 |
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| n/a |
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| Name | BDBM50118479 |
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| Synonyms: | 2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyric acid | CHEMBL334842 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H9N3O3S |
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| Mol. Mass. | 203.219 |
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| SMILES | N[C@H](CCc1ns[nH]c1=O)C(O)=O |
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| Structure | 
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