| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1B adrenergic receptor |
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| Ligand | BDBM50022722 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_34311 (CHEMBL648096) |
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| Ki | 9600±n/a nM |
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| Citation |  Altenbach, RJ; Khilevich, A; Meyer, MD; Buckner, SA; Milicic, I; Daza, AV; Brune, ME; O'Neill, AB; Gauvin, DM; Cain, JC; Nakane, M; Holladay, MW; Williams, M; Brioni, JD; Sullivan, JP N-[3-(1H-imidazol-4-ylmethyl)phenyl]ethanesulfonamide (ABT-866, 1),(1) a novel alpha(1)-adrenoceptor ligand with an enhanced in vitro and in vivo profile relative to phenylpropanolamine and midodrine. J Med Chem45:4395-7 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1B adrenergic receptor |
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| Name: | Alpha-1B adrenergic receptor |
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| Synonyms: | ADA1B_HUMAN | ADRA1B | Adrenergic alpha1B | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1B-adrenoceptor | Alpha 1B-adrenoreceptor | Alpha-1B adrenergic receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 56862.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35368 |
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| Residue: | 520 |
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| Sequence: | MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAI
VGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDI
WAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGP
LLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAG
VMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVV
GMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFV
RILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRT
LPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLT
EPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF
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| BDBM50022722 |
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| n/a |
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| Name | BDBM50022722 |
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| Synonyms: | (+)2-Amino-1-phenyl-propan-1-ol | (1R, 2R)-2-Amino-1-phenyl-propan-1-ol | (1R, 2S)-2-Amino-1-phenyl-propan-1-ol | (1S, 2R)-2-Amino-1-phenyl-propan-1-ol | (1S, 2S)-2-Amino-1-phenyl-propan-1-ol | 2-Amino-1-phenyl-propan-1-ol | Biphetap | Bromanate | Bromatapp | CHEMBL136560 | Codamine | Contac | Demazin | Dimetane-DC | Dimetapp | Drize | Hycomine | Norephedrine, (+) | Norephedrine, (-) | Ornade | PHENYLPROPANOLAMINE | Pseudonorephedrine, (+) [cathine, (+)] | Pseudonorephedrine, (-) [cathine, (-)] | Tavist-D | Triaminic-12 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H13NO |
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| Mol. Mass. | 151.2056 |
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| SMILES | CC(N)C(O)c1ccccc1 |
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| Structure | 
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