| Reaction Details |
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 | Report a problem with these data |
| Target | Nicotinamide N-methyltransferase |
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| Ligand | BDBM50557606 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2059712 (CHEMBL4714713) |
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| IC50 | 74±n/a nM |
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| Citation |  Sabnis, RW Novel Pyrimidine-5-carboxamide Compounds as NNMT Inhibitors for Treating Diabetes. ACS Med Chem Lett12:538-539 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nicotinamide N-methyltransferase |
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| Name: | Nicotinamide N-methyltransferase |
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| Synonyms: | NNMT | NNMT_HUMAN | Nicotinamide N-methyltransferase | Nicotinamide N-methyltransferase (NNMT) |
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| Type: | Protein |
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| Mol. Mass.: | 29571.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 264 |
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| Sequence: | MESGFTSKDTYLSHFNPRDYLEKYYKFGSRHSAESQILKHLLKNLFKIFCLDGVKGDLLI
DIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPEAFDWSPVVTYVCDLEGN
RVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLDAACPDLPTYCRAL
RNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAVEAAVKEAGYTIEWFEVISQ
SYSSTMANNEGLFSLVARKLSRPL
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| BDBM50557606 |
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| n/a |
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| Name | BDBM50557606 |
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| Synonyms: | CHEMBL4791213 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H24FN5O2 |
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| Mol. Mass. | 325.3818 |
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| SMILES | CC(C)(F)CCCNc1ncc(C(N)=O)c(NC2(CO)CC2)n1 |
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| Structure | 
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