| Reaction Details |
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 | Report a problem with these data |
| Target | Adenylate cyclase type 5 |
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| Ligand | BDBM50119854 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_213256 (CHEMBL821464) |
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| IC50 | 96000±n/a nM |
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| Citation |  Levy, D; Bao, M; Tomlinson, J; Scarborough, R Hydroxamate based inhibitors of adenylyl cyclase. Part 2: the effect of cyclic linkers on P-site binding. Bioorg Med Chem Lett12:3089-92 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenylate cyclase type 5 |
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| Name: | Adenylate cyclase type 5 |
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| Synonyms: | ADCY5 | ADCY5_HUMAN | Adenylate cyclase | Adenylate cyclase type V |
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| Type: | PROTEIN |
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| Mol. Mass.: | 138919.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_31732 |
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| Residue: | 1261 |
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| Sequence: | MSGSKSVSPPGYAAQKTAAPAPRGGPEHRSAWGEADSRANGYPHAPGGSARGSTKKPGGA
VTPQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR
GAASGGSTRAPPAGGGGGSAAAAASAGGTEVRPRSVEVGLEERRGKGRAADELEAGAVEG
GEGSGDGGSSADSGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQS
SLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILIMAVLCNRAAFHQDHMGL
ACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSAL
HLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLH
SQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTS
LASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEM
GMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGK
AGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMN
RQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFL
GRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQI
TIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKIVRSKMNSTLVGVF
TITLVFLAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVAESAVNYSLGDEQGFCGSP
WPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIVEVPGVTLFDNADL
LVTANAIDFFNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKL
QATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANF
SEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTY
DKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWG
NTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPL
S
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| BDBM50119854 |
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| n/a |
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| Name | BDBM50119854 |
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| Synonyms: | 2-{[(1R,4S)-4-(6-amino-9H-purin-9-yl)cyclopent-2-en-1-yl]oxy}-N-hydroxyacetamide | CHEMBL105636 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H14N6O3 |
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| Mol. Mass. | 290.278 |
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| SMILES | Nc1ncnc2n(cnc12)[C@H]1C[C@@H](OCC(=O)NO)C=C1 |c:21| |
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| Structure | 
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